A two-day event will take place at the Faculté de Médecine Paris Descartes in Paris, on May 17-18, in order to assess and present what has been accomplished during Lifepath’s first year of research, and to discuss the future perspectives of the project. Lifepath is an EU-funded project aimed to face one of the major challenges for modern societies: the dramatic inequalities in wellbeing and health conditions, and their underlying social and economic differences. Healthy ageing begins at conception, if not before, and it involves a progressive differentiation across social groups. A series of biological changes underpin the effect of complex environmental, behavioural and social patterns on health, and can be traced with modern research technologies. By investigating the biological consequences of socio-economic inequalities, Lifepath aims to lay ground for the development of future health policies and strategies. “The project is highly innovative since it links together social sciences, biology and medicine”, says Paolo Vineis, coordinator of the project. “We are currently exploring not only the impact of low socio-economic status on ageing and mortality, but also on intermediate molecular events such as functional changes in DNA and metabolism”.

The press conference will start at 1:00 PM CET (GMT+2:00) on the Zoom platform and will be attended by some members of the Lifepath project:
- Paolo Vineis (Imperial College, United Kingdom)
- Marcel Goldberg (INSERM, France)
- John Mackenbach (The Erasmus University in Rotterdam, Netherlands)

If you are interested in participating, you may send your confirmation to Luca Carra (carra@zadig.it).

Where
Faculté de Médecine
Paris Descartes
15 rue de l'Ecole de médecine,
75005 Paris (métro Odéon)
Salle du Conseil

When
Tues. 17th – Wed. 18th May 2016
Tuesday 9:00 – 17:30 Wednesday 9:00 – 13:30

Goals: to assess the 1’s year’s actions on Lifepath Project and plan activities for year 2

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Tuesday 17th

Morning session
09:30 – 10:00 General Introduction – Paolo Vineis & Marcel Goldberg
10:00 – 11:00 Keynote lecture – Experimental induction of stress and epigenetic changes in animal models Vincent Cunliffe, Sheffield University
11:00 – 12:00 Overview and state of advancement of the project - Paolo Vineis

[Part one – the data]

12:00 – 12:30 Educational disparities in life and health expectancy in Europe (WP2) - Wilma Nusselder, Johan Mackenbach
12:30 – 13:00 Discussion
13:00 – 14:00 Lunch

Afternoon session
14:00 – 15:00 Analysis of the “decline” phase: results and perspectives (with discussion) – Cristian Carmeli, Mika Kivimaki and Silvia Stringhini
15:00 – 16:00 Analysis of the “build-up” phase: results and perspectives (with discussion) – Richard Layte, Cathal McCrory
16:00 – 16:30 Coffee Break

[Part two – the biomarkers]

16:30 – 17:00 Update on WP4: blood samples from Ireland and Portugal, activities of the laboratories – Paolo Vineis, Silvia Polidoro
17:00 – 17:15 Repository of already measured biomarkers, and results of methylation analyses in EPIC and MCCS – Paolo Vineis
17:15 – 17:30 On-going analyses of inflammatory markers – Michelle Kelly, Cyrille Delpierre
17:30 – 18:00 Administrative issues – Terrence Simmons

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Wednesday 18th

[Part three – the policies]

Morning session
09.00 – 09:30 How will we translate all this into policy? – Mika Kivimaki
09:30 – 10:00 The conditional cash transfer experiments: introduction and re-analyses of the NYC data – Mauricio Avendano
10:00 – 10:30 A multi-center Earned Income Tax Credit experiment. Plan for biomarker collection – Peter Muennig
10:30 – 11:00 Coffee Break

[Part four – methods and dissemination]
11:00 – 12:00 Longitudinal statistical models (with examples and discussion) – Michelle Kelly, Cyrille Delpierre, Marc Chadeau-Hyam
12:00 – 12:30 Dissemination – Luca Carra
12:30 – 13:30 General discussion and tasks for 2016 (led by P Vineis)

[End of Annual meeting]

13:30 – 14:30 Lunch

Afternoon session
14:30 – 16:30 Review and integration meeting WPs 3, 4, 7 – organized by Michelle Kelly-Irving
14:30 – 16:30 Meeting of the International Advisory Board (Parallel meeting)
16:30 – 17:30 In-person meeting of the Project Steering Board

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Invitees in addition to partners:

• Jennifer Dowd
• Daniela Del Boca
• Mel Bartley
• International Advisory Board (David Blane, Elina Hemminki, Laura Fratiglioni, Béatrice Fervers)

Faculté de Médecine Paris Descartes in Paris